The GDC KinReport
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What is the KinReport?
People who register their dogs with GDC agree to make all the genetic screening information for each dog available to breeders, owners and researchers who can use that knowledge to help improve the health of purebred dogs.
GDC has closed all its registries except Eye and Tumor, and is merging its data bases with OFA. However, evaluation information on all dogs registered with GDC is still available through the KinReports. From 1990 to 2002, GDC registered information on more genetic diseases than any other single national registry: the GDC registries included orthopedic, eye, hearing, skin, and cardiac disease, as well as cancer and others. (The number and type of evaluations will vary from one dog to another).
GDC can provide users with a single reportthe KinReport that includes genetic health information on the dog in question and all of its close relatives who are also registered with GDC.The KinReport shows all available evaluations (affected and unaffected) on each of the several dogs in the report.
Knowing the evaluations or certifications for a particular dog (the phenotype) is of very little help in predicting that dog's risk for acquiring or handing down the genes for a particular genetic disease. To assess the genetic health (the genotype) of a particular dog, you need information on its closest relativessiblings, half-siblings, offspring, parents, aunts and uncles.
A KinReport provides all evaluation information in the GDC registry on the following:
A GDC KinReport on a particular dog links it with all close relatives registered in the database, providing genotypic information for an entire family of dogs. The number of dogs in the report depends on the committment of breeders and owners to registering as many related dogs as possible.
Because the KinReport shows the prevalence of genetic disease in a dog's parents, siblings, litter mates, half-siblings and offspring, breeders and owners can assess a particular dog's risk for acquiring or handing down genetic disease.
That means if you are a puppy buyer who wants to see, in black and white, what the evaluations for hip dysplasia are for the close relatives of your dog, you may be able to find that information in the GDC KinReport.
If you are a breeder with a concern about a single-gene disease like SA (sebaceous adenitis), and you need to evaluate several sires to reduce the risk of breeding to a carrier, you may be able to find that information also in the KinReport. (The completeness of any KinReport is limited by the number of dogs registered in a particular family).
With several KinReports covering the branches of a dog's family, you may have the information needed to draw that dog's genetic pedigree. As the number of dogs in a particular breed in the GDC registry grows large enough, GDC can create KinReports to give breeders and owners for the first time a full picture of the genetic health of a particular dog and its family. With the help of a genetic counselor, breeders and owners can assess a dog's risk of acquiring, or handing down, genetic disease.
For each dog's lineage, the KinReport provides a list of all positive evaluations (unaffected phenotypes) and negative evaluations (disease-affected phenotypes), submitted by veterinarians following the high standards of protocols approved by GDC. To support scientifically-sound decisions, the statistical pattern of the entire lineage should be examined, to detect the probability of unaffected phenotypes that are really "silent carriers" for a disease-related genotype.
To order a KinReport online: