S.I.G.H.T. Registry (Sealyham Terriers)
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The Sealyham SIGHT Registry Brochure
and Genetic Disease
What can you do?
What is the
of Lens Luxation
Symptoms to watch for (call your vet immediately!!):
What is Lens
The lens at first will move from its normal position (called subluxation). If the fibers break, the lens will slip, or luxate, from position, and may move either forward or backward inside the eye.
When the lens slips from position it often blocks the flow of fluid in the eye, and the resulting rise in pressure may cause glaucoma which will result in irreparable damage to the retina and optic nerve within 72 hours.
If the eye is not damaged by glaucoma, most dogs will still have some vision even with the lens surgically removed. In many cases, the lens in the second eye may be still partially attached, and drug therapy to treat the glaucoma may help to slow the luxation of that lens.
1) Eye Exam (optional): You can register your dog without an eye exam. Simply fill out the SIGHT registration form and send it to the registry.
However, we strongly encourage eye exams for Sealys every 1-2 years. You can have your veterinarian do a basic eye exam.
Or you can schedule a CERF (Canine Eye Registration Foundation) eye exam for your dog. This is a standand exam done by any ACVO ophthalmologist (American College of Veterinary Ophthalmologists). ACVO Clinic List (Locate a veterinary opthalmologist in your state) The cost is usually $20-40.
If there is no ophthalmologist in your area, ask your regular veterinarian for an exam. You can register your dog with SIGHTwith a standard veterinary eye exam, but this is not a substitute for a CERF exam by a veterinary ophthalmologist.
2) SIGHT Application Form: If you need a form, click here to download and print. Complete the form and send it in with the fee. If your dog has had an eye exam, ask your vet for a letter stating results of the exam, or if CERF exam, ask for the CERF form, to include with the SIGHT registration form.
3) Registration Cost: The first time you register your dog, the fee is $10. The fee is $5 for subsequent updates of your dog’s eye exams (every 1-2 years). There is no charge for registering a dog affected with lens luxation.
4) Blood Sample: If your dog is affected with lens luxation or closely related to an affected dog (sibling, offspring or parent), it is very important to send a blood sample to the DNA research project at the University of Missouri. For instructions see the SIGHT Blood Sample Submission form.
How will breeders use the registry to help reduce the risk of lens luxation?
A breeder who is interested in a dog from a particular family group will be able to create what is known as a genetic pedigree of that group. The genetic pedigree shows clearly where the affected dogs are in the family, and with that knowledge, the breeder can determine which dogs are probably carriers, and what the carrier risk is for other dogs. GDC will provide information, resources and access to canine genetic counselors to help breeders with complex risk assessments and breeding questions.
What is the
does the genetics of lens luxation work?
Without a DNA test, the only way to positively identify a carrier is to breed it to another carrier. When both parents are carriers, some of the puppies will inherit the genes from each parent, and will become affected several years later. Several other puppies will inherit just one copy of the gene and will be carriers. And the remaining puppies will not inherit the gene.
The parents of an affected dog are assumed to be carriers. And all the offspring of an affected dog are assumed to be carriers. If a dog is a carrier, but has many excellent traits, that dog can still be bred, but only under very strict guidelines. The dog must not be bred to another carrier, and all of the dog’s offspring must be presumed to be carriers until proven otherwise, either by a DNA test, or by several test breedings to a known carrier which produce no affecteds. (Due to the long onset time of lens luxation, test breeding may not be practical.)
(Institute for Genetic Disease Control)